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Eucalyptus camaldulensis is a rapidly growing tree with a variety of applications. The present study aims to investigate the effect of Eucalyptus oil in mice as orally and inhaling, including the side effects, and the pathological changes in the respiratory system. Eucalyptus oil was obtained by extracting the leaves of E. camaldulensis using hydro-distillation. The animals were divided into control group, group inhaled eucalyptus oil, group administered orally, and a mixing group that administered and inhaled eucalyptus oil. When animals administered the oil showed clinical signs and a weight loss. In the hematological parameters, there was an increase in white blood cells and a decrease in red blood cells, hemoglobin and blood platelets. In the inhalation group, no pathological changes were found. The pathological changes in the trachea and lung in group administered eucalyptus oil, and group inhaled eucalyptus oil, no histological changes occurred. An increase in the lumen of the trachea also occurred in experiment animals. It was found that inhalation of eucalyptus oil expands the tracheal lumen and reduces mucus secretion and thus can be used to treat asthma, cough, common colds, obstructive pulmonary and sinusitis, and eucalyptus oil is moderately toxic when administered orally.


Inhalation Trachea Lung Hematological parameters Body weight.

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How to Cite
ALNAJI, Z. M., & ALI, A. K. (2021). Histological and hematological study of eucalyptus oil in the respiratory tract of mice. Iranian Journal of Ichthyology, 8, 397–411.


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